# The injection that could replace weeks of chemo: in vivo CAR-T enters the autoimmune clinic - Date: 2026-04-15 - Category: Biotech & Life Sciences Standard CAR-T for autoimmune disease requires weeks of chemotherapy and ICU-level care. An injection without preconditioning just showed deep B-cell depletion in lymph node tissue for the first time, with a manufacturing scale that could make it a platform, not a trial. ---